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This error happens when a Page tries to reply to a Facebook message/conversation, while this conversation has already been terminated. Facebook conversations initiated in Guest mode can be terminated by the user or can be closed automatically after 24 hours. You won't be able to reply to such a message anymore.

It could also happen when trying to answer to a DM received from another Facebook Page.

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This error happens when a comment has already been responded to privately - directly on Facebook or with another 3rd party tool. You can only respond privately to a comment once.

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This error happens when a user's privacy settings prevent others from responding privately to their comments, therefore you won't be able to reply privately to the given comment.

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This error happens when a Page's ability to send commerce messages has been temporarily disabled. Facebook doesn't disclose any details on why it has disabled the Page, nor when the restriction is going to be lifted. The only recommendation for you is to make sure you're compliant with Messenger Platform Policy and try again later.

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This error happens when due to permissions we aren't allowed to comment on your behalf - most likely the post has audience restriction that doesn't allow us to actually publish the comment.

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This error happens when there is a temporary issue with API, due to downtime. The recommendation is to wait and retry the operation after a while.

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This is shown when you try to send a message to a Facebook user, who prevents you from sending the message. To be more precise, this user has disabled the Apps Platform. You will need to reply to the message natively.

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Since Messenger allows users to opt out of conversations, it is possible that the user being replied to has changed their settings/preferences since starting the conversation. Or the user has removed the Messenger app. The recommendation is to try replying natively from Facebook and see if this works.

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It happens when an Instagram user disables @mentions in their Privacy - Mentions settings, which prevents other accounts to mention them in captions, comments, etc. It results in this error on our side, when you are replying to comments. The solution is to leave out the @mention part from the comment.

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The error message might indicate that Instagram's automated systems may have considered the reply as spam (although it might not be). Instagram doesn't disclose any further information on this since any details could potentially lead to circumventing the rules.

We recommend to try the following to see if you are able to reply:

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This error happens when you try to send an Instagram message (DM) in the conversation that was already deleted by “thread owner” (= recipient, i.e. your Business profile).

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This error occurs when an ad has been updated. Each time an ad is updated, all old comments made before this change will not be removable or able to be replied to from any 3rd party tool like Agorapulse. Instagram hasn't provided us with a way to sync ad comments properly once ad updates have been made. We'll continue to sync new comments that you will be able to reply to or delete until the ad is updated again.

As a workaround, you can open the comment up natively and take action there.
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This error can occur when an access token has expired, been revoked, or is otherwise invalid. Try to refresh the token in Organization settings > Social profiles.

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Since there are no further details in the error code, the only recommendation is to retry the action again later.

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There are several reasons why you might get this error when replying to an ad comment. This may be because the post is a dynamic ad, it has been updated since it's launch, or the ad no longer exists on Instagram. You can simply click on the View on Instagram button, which will take you directly to the comment on Instagram where you can reply.

Recommendation

Try to modify your comment by changing its wording or rephrasing part of it. Also, avoid using the same reply to multiple comments as this could be seen as an 'automated' reply. Another suggestion is to avoid using too short of replies or replies consisting of smileys only.

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It happens when you try to send a message to a user to whom you're not allowed to send a message - for example because they're not following you or they have blocked you, etc. There is no workaround - you won't be able to send message to such user.